2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

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Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W099331R
    Monoethylglycinexylidide (hydrochloride) (Standard)
    Benfuracarb (Standard) is the analytical standard of Benfuracarb. This product is intended for research and analytical applications. Benfuracarb is a broad-spectrum carbamate insecticide with crop protection activity. Benfuracarb is used to control springtails, aphids, and other pests, typically on sugar beet crops. Benfuracarb exhibits toxicity to humans and aquatic organisms. Benfuracarb exposure to zebrafish embryos resulted in a reduction in the body length of zebrafish larvae. Superoxide dismutase (SOD) activity was significantly increased after Benfuracarb treatment. Benfuracarb also interfered with the transcriptional levels of marker genes associated with early embryonic development.
    Monoethylglycinexylidide (hydrochloride) (Standard)
  • HY-137772R
    Captopril EP Impurity E (Standard)
    Captopril EP Impurity E (Standard) is the analytical standard of Captopril EP Impurity E. This product is intended for research and analytical applications. Captopril EP Impurity E is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM).
    Captopril EP Impurity E (Standard)
  • HY-162297
    4-(Sulfooxy)benzoic acid
    4-(Sulfooxy)benzoic acid is a sulfated phenolic acid found in C. elegans. 4-(Sulfooxy)benzoic acid is a metabolite of ethyl para-hydroxybenzoate and several flavonoids.
    4-(Sulfooxy)benzoic acid
  • HY-169851
    JANEX-1-M
    JANEX-1-M is a metabolite of JANEX-1 (HY-15508). JANEX-1 is a JAK3 specific inhibitor, which can effectively inhibit mast cell degranulation and the release of pro-inflammatory mediators.
    JANEX-1-M
  • HY-43670
    Chlorthalidone impurity
    Chlorthalidone impurity is a metabolite of Chlorthalidone (HY-15833). Chlorthalidone is a thiazide-like diuretic used to treat hypertension.
    Chlorthalidone impurity
  • HY-101397R
    Allopurinol riboside (Standard)
    Cholic acid (Standard) is the analytical standard of Cholic acid. This product is intended for research and analytical applications. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid is orally active.
    Allopurinol riboside (Standard)
  • HY-125594
    T-1095A
    T-1095A is an active metabolite of T-1095 (HY-106158) (an SGLT inhibitor).
    T-1095A
  • HY-134137
    Donepezil N-oxide
    		Control
    Donepezil N-oxide, a metabolite of Donepezil (HY-14566), is human erythrocyte acetylcholinesterase (AChE) inhibitor.
    Donepezil N-oxide
  • HY-N9484S
    Menthofuran-13C2
    Menthofuran-13C2 is 13C labeled Menthol (HY-N1369). Menthol is an analgesic and TRPM8 modulator. TRPM8 is a cold temperature sensing ion channel, and Menthol can regulate TRPM8 to exert analgesic and anti-irritation mechanisms. Menthol stimulates cold receptors and produces a cooling sensation by inhibiting Ca++ currents in neuronal cell membranes. Menthol also improves oral nicotine rejection in mice.
    Menthofuran-<sup>13</sup>C<sub>2</sub>
  • HY-172057
    4-Fluoromethcathinone metabolite hydrochloride
    4-Fluoromethcathinone metabolite hydrochloride is a metabolite of 4-Fluoromethcathinone.
    4-Fluoromethcathinone metabolite hydrochloride
  • HY-131450
    1α,25-Dihydroxyprevitamin D3
    		Control
    1α,25-Dihydroxyprevitamin D3 is the precursor of Vitamin D3.
    1α,25-Dihydroxyprevitamin D3
  • HY-W011596
    2-Amino-2'-chloro-5-nitrobenzophenone
    		Control
    2-Amino-2'-chloro-5-nitrobenzophenone is a precursor in the synthesis of benzodiazepines. 1 2-Amino-2’-chloro-5-nitrobenzophenone is also a hydrolysis product of Clonazepam.
    2-Amino-2'-chloro-5-nitrobenzophenone
  • HY-148002
    1'-Hydroxy Midazolam-β-D-glucuronide
    1'-Hydroxy Midazolam-β-D-glucuronide is a β-D-glucuronide that acts as a drug metabolite, human urine metabolite, and human serum metabolite.
    1'-Hydroxy Midazolam-β-D-glucuronide
  • HY-157253
    13(S)-HODE-biotin
    13(S)-HODE is the lipoxygenase metabolite of Linoleic acid (HY-N0729). 13(S)-HODE modulates the platelet-activating factor, leukotriene B4, and formyl-Met-Leu-Phe-induced calcium influx in human polymorphonuclear leukocytes.
    13(S)-HODE-biotin
  • HY-32350R
    Ercalcitriol (Standard)
    Ercalcitriol (Standard) is the analytical standard of Ercalcitriol. This product is intended for research and analytical applications. Ercalcitriol (1α,25-Dihydroxy Vitamin D2) is an active metabolite of vitamin D2.
    Ercalcitriol (Standard)
  • HY-Y0469R
    1-Aminohydantoin (hydrochloride) (Standard)
    1-Aminohydantoin (hydrochloride) (Standard) is the analytical standard of 1-Aminohydantoin (hydrochloride). This product is intended for research and analytical applications. 1-Aminohydantoin hydrochloride is a major metabolite of nitrofurantoin in animal tissues and can be used as a standard for the determination of residues of veterinary agents in meat, milk et.al. 1-Aminohydantoin hydrochloride covalently binds to tissue proteins and is released from the tissues under slightly acidic conditions and derivatized with 2-nitrobenzaldehyde to form nitrophenyl derivatives of AHD before detection.
    1-Aminohydantoin (hydrochloride) (Standard)
  • HY-N8210R
    Homoeriodictyol (Standard)
    Benzofenap (Standard) is the analytical standard of Benzofenap. This product is intended for research and analytical applications. Benzofenap is a herbicide.
    Homoeriodictyol (Standard)
  • HY-138573
    N-Acetyl Adamantamine
    N-Acetyl Adamantamine (1-Acetamidoadamantane) is a major metabolite of Amantadine (HY-B0402)[1].
    N-Acetyl Adamantamine
  • HY-137768
    Captopril EP Impurity B
    Captopril EP Impurity B is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM).
    Captopril EP Impurity B
  • HY-I0454
    Rivaroxaban EP Impurity I
    Rivaroxaban EP Impurity I (Imp I) is the impurity reference for Rivaroxaban EP.
    Rivaroxaban EP Impurity I
Cat. No. Product Name / Synonyms Application Reactivity